(A) Tay-Sachs disease
(B) Gaucher’s disease
(C) Niemann-Pick disease
(D) Fabry’s disease
Author:
All of the following statements about generalized gangliosidosis are true except?
(A) It results from deficiency of GM1-β-
Gangliosidase
(B) Breakdown of GM1 ganglioside is impaired
(C) GM2 ganglioside accumulates in liver and
elsewhere
(D) It leads to mental retardat
The enzyme deficient in metachromatic leukodystrophy is?
(A) Arylsulphatase A
(B) Hexosaminidase A
(C) Ceramidase
(D) Sphingomyelinase
β -Galactosidase is deficient in?
(A) Fabry’s disease
(B) Krabbe’s disease
(C) Gaucher’s disease
(D) Metachromatic leukodystrophy
Free fatty acids released from adipose tissue are transported in blood by?
(A) Albumin
(B) VLDL
(C) LDL
(D) HDL
De novo synthesis and oxidation of fatty acids differ in the following respect:
(A) Synthesis occurs in cytosol and oxidation in
mitochondria
(B) Synthesis is decreased and oxidation
increased by insulin
(C) NADH is required in synthesis and FAD in
oxidation
(D) Malonyl CoA is formed during oxidation but
not during synthesis
Hypocholesterolaemia can occur in?
(A) Hyperthyroidism
(B) Nephrotic syndrome
(C) Obstructive jaundice
(D) Diabetes mellitus
Prostaglandins decrease all of the following except?
(A) Gastric acid secretion
(B) Blood pressure
(C) Uterine contraction
(D) Platelet aggregation